In this paper, the effect of using SH-A process to treat Atorvastatin Calcium pharmaceutical wastewater is studied. This study mainly focuses on the effect of temperature on the SH-A process. The experimental results show that: the SH-A process has an effective removal of COD and -N; temperature is key factor of the treatment effects. Under the given conditions, the COD removal efficiency improved significantly with the increasing system temperature; the maximum COD removal rate occurred when the temperature reached 35˚C; continued to rise system temperature, COD removal rate decreased. In terms of the -N, with the increase of the system temperature, the removal rate was significantly improved; when the temperature reached 29˚C, -N removal rate reached 100%; continued to rise the temperature, the removal rate remained unchanged. According to the experimental results, the optimal tempera- ture for SH-A process to treat the Atorvastatin Calcium pharmaceutical wastewater should be 35˚C.