In Vitro Evaluation of the Potential Anti Mycoba-Cterium Tuberculosis Activity of 29 Chinese Traditional Medicinal Plants
Abstract: Tuberculosis is one of common infectious diseases that has been difficult to control so far and has been on the rise in recent years. Chinese herbal medicine is an important natural resource for the discovery of new drug, and China has a wealth of natural medicine resources. In this experiment, 29 traditional Chinese medicines were selected for the screening of anti-M tuberculosis H37Rv and BCG respectively. The results indicated that 14 kinds of herbs showed powerful activity against Myco-bacterium tuberculosis H37Rv and BCG. Among them, 9 kinds of Chinese herbal medicine exhibited synergistic antibacterial effect combined with isoniazid and rifampicin respectively. In addition, it was first discovered that the Sanjiaotiao (Chinese name) had anti-Myco bacterium tuberculosis activity. The study laid the foundation for the discovery of the new skeleton of anti-Mycobacterium tuberculosis drug.
文章引用: 韩立芬 , 宋善敏 , 邓伟 , 甘梦兰 , 王仁凤 , 杨再昌 (2017) 体外评价29种中药的抗结核分枝杆菌活性。 药物化学， 5， 39-44. doi: 10.12677/HJMCe.2017.53006
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