徽菇多糖的研究与开发
Research and Development of Polysaccharides from Anhui Mushrooms

作者: 高绍璞 :安徽正邦司法鉴定所,安徽 合肥; 周礼元 :合肥市产品质量监督检验所,安徽 合肥;

关键词: 徽菇活性多糖研发产业化Anhui Mushrooms (AM) Polysaccharides Research and Development Industrialization

摘要:
徽菇,其味鲜美,历来为徽菜中的上等食材。徽菇多糖作为徽菇中重要的活性物质,具有多种药理活性,其开发利用前景广阔。本文在对徽菇多糖相关文献进行深入分析的基础上,阐述徽菇多糖的研究进展,揭示了徽菇多糖产业发展态势。目前徽菇多糖的研究开发处于“发展期”,发展轨迹良好;但同时,徽菇多糖应用性开发的产业化不足,徽菇的天然资源优势未能转化为徽菇多糖的产业优势。作者在此基础上提出了徽菇多糖产业化开发的潜在产品群及其产业化前景,以期为徽菇资源的多途径利用开发,提升徽菇资源价值提供思路。

Abstract: As a mountain treasure, Anhui mushrooms (AM) have stood in the finest raw materials due to its palatable nature. As a critical and active substance, AM polysaccharide has a variety of pharmacological activities and bright prospect for development and utilization. Based on the analysis of the relevant literature for AM polysaccharide, herein we describe the research progress of AM polysaccharide as well as reveal its industrial development and utilization. It is suggested that at present the research and development of AM polysaccharide is in the “evolution period” with superb potential. Whereas meanwhile, AM polysaccharide lacked development at the industrialization, and its natural resources have not been transformed into industry advantage. On the basis of above, this study puts forward the potential product group and its industrialization development prospect of AM polysaccharide, and anticipates developing and utilizing AM resources in multi way, subsequently providing useful ideas and for improving AM resources value.

文章引用: 高绍璞 , 周礼元 (2017) 徽菇多糖的研究与开发。 自然科学, 5, 268-273. doi: 10.12677/OJNS.2017.53037

参考文献

[1] 朱国晔, 谢奇. 来自徽菇之乡的报告[J]. 中国食用菌, 1992(5): 43.

[2] 朱国晔, 谢奇. 徽菇[J]. 中国食用菌, 2000(2): 13.

[3] Djordjevic, B., Škugor, S., Jørgensen, S.M., et al. (2009) Modulation of Splenic Immune Responses to Bacterial Lipopolysaccharide in Rainbow Trout (Oncorhynchus mykiss) Fed Lentinan, a Beta-Glucan from Mushroom Lentinula edodes. Fish & Shellfish Immunology, 26, 201-209.
https://doi.org/10.1016/j.fsi.2008.10.012

[4] Zhang, L., Li, X., Xu, X., et al. (2005) Correlation between Antitumor Activity, Molecular Weight, and Conformation of Lentinan. Carbohydrate Research, 340, 1515-1521.
https://doi.org/10.1016/j.carres.2005.02.032

[5] Thetsrimuang, C., Khammuang, S., Chiablaem, K., et al. (2011) Antioxidant Properties and Cytotoxicity of Crude Polysaccharides from Lentinus polychrous Lév. Food Chemistry, 128, 634-639.
https://doi.org/10.1016/j.foodchem.2011.03.077

[6] Bisen, P.S., Baghel, R.K., Sanodiya, B.S., et al. (2010) Lentinus edodes: A Macrofungus with Pharmacological Activities. Current Medicinal Chemistry, 17, 2419-2430.
https://doi.org/10.2174/092986710791698495

[7] 金茜, 朱彬, 罗宿星, 曾启华, 张世仙, 魏福伦. 食用菌多糖生物活性的研究进展[J]. 遵义师范学院学报, 2010, 12(4): 75-78.

[8] 孟庆恒, 赵建英. 食用菌的药用价值[J]. 生物学通报, 1991(1): 27.

[9] Zhang, L., Zhang, X., Zhou, Q., Zhang, P., Zhang, M. and Li, X. (2001) Triple Helix of β-D-Glucan from Lentinus edodes in 0.5 M NaCl Aqueous Solution Characterized by Light Scattering. Polymer Journal, 33, 317-321.
https://doi.org/10.1295/polymj.33.317

[10] Guo, Z., Hu, Y., Wang, D., Ma, X., Zhao, X., Zhao, B., et al. (2008) Sulfated Modification Can Enhance the Adjuvanticity of Lentinan and Improve the Immune Effect of ND Vaccine. Vaccine, 27, 660-665.
https://doi.org/10.1016/j.vaccine.2008.11.038

[11] 朱新荣, 邓辉, 童军茂, 等. 香菇多糖Le-2的化学修饰对SP-2小鼠肿瘤细胞抑制率的影响[J]. 石河子大学学报(自科版), 2008, 26(5): 603-607.

[12] 吴学谦, 贺亮, 程俊文, 等. 香菇多糖的化学修饰及结构表征[J]. 天然产物研究与开发, 2009, 21(6): 934-938.

[13] 丁丁. 香菇多糖及其衍生物抑制AFB-1合成及其抑制机理研究[D]: [硕士学位论文]. 杨凌: 西北农林科技大学, 2013.

[14] 钱慈. 香菇深层发酵及其多糖的分离纯化、磷酸化研究[D]: [硕士学位论文]. 阿拉尔: 塔里木大学, 2013.

[15] Mizuno, T., Ykohlui, P., Kinoshita, T., et al. (1996) Antitumor Activity and Chemical Modification of Polysaccharides from Niohshimeji Mushroom, Tricholma giganteum. Bioscience, Biotechnology, and Biochemistry, 60, 30-33.
https://doi.org/10.1271/bbb.60.30

[16] Chung, M.J., Park, J.K. and Park, Y.I. (2012) Anti-Inflammatory Effects of Low-Molecular Weight Chitosan Oligosaccharides in IgE-Antigen Complex-Stimulated RBL-2H3 Cells and Asthma Model Mice. International Immunophar- macology, 12, 453-459.

[17] Zhang, Z., Wang, X., Mo, X., et al. (2013) Degradation and the Antioxidant Activity of Polysaccharide from Enteromorpha linza. Carbohydrate Polymers, 92, 2084-2087.

[18] 任瑞, 马海乐, 刘斌, 等. 超声降解香菇多糖及其体外抗氧化活性的研究[J]. 安徽农业科学, 2008, 36(17): 7061- 7062.

[19] Minato, K., Kawakami, S., Nomura, K., et al. (2004) An Exo β-1, 3-Glucanase Synthesized De Novo Degrades Lentinan during Storage of Lentinule edodes and Diminishes Immunomodulating Activity of the Mushroom. Carbohydrate Polymers, 56, 279-286.

[20] 任明. 复合多糖抗辐射和抗肿瘤作用及其机制研究[D]: [博士学位论文]. 长春: 吉林大学, 2014.

[21] Hamuro, J., Takatsuki, F., Suga, T., Kikuchi, T. and Suzuki, M. (1994) Syenergistic Antimetastatic Effects of Lentinan and Interleukin 2 with Pre- and Post-Operative Treatments. Japanese Journal of Cancer Research, 85, 1288-1297.
https://doi.org/10.1111/j.1349-7006.1994.tb02942.x

[22] Drandarska, I., Kussovski, V., Nikolaeva, S. and Markova, N. (2005) Combined Immunomodulating Effects of BCG and Lentinan after Intranasal Application in Guinea Pigs. International Immunopharmacology, 5, 795-803.

[23] 魏倩婷. 香菇酚类物质的提取及功能学特性的研究[D]: [硕士学位论文]. 福州: 福建农林大学, 2011.

[24] Chibata, I., Okumura, K., Takeyama, S., et al. (1969) Lentinacin: A New Hypocholesterolemic Substance in Lentinus Edodes. Experientia, 25, 1237-1238.
https://doi.org/10.1007/BF01897467

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