香砂脘痛胶囊质量研究
Quality Standard of Xiangshawantong Capsule

作者: 辛振杰 :罗定市中医院,广东 罗定; 饶秋红 :广州中医药大学第一临床医学院,广东 广州;

关键词: 香砂脘痛胶囊质量薄层色谱高效液相色谱法Xiangshawantong Capsule Quality TLC HPLC

摘要:
目的:探讨建立控制香砂脘痛胶囊质量的方法。方法:采用薄层色谱法(TLC)对川芎、当归和赤芍药材进行定性鉴别,采用高效液相色谱法(HPLC)对牡荆苷进行含量测定。结果:TLC特征斑点明显清晰、专属性强。牡荆苷在0.0576~0.2880 μg (r = 0.9998)间具有良好的线性关系,平均回收率分别为99.73% (RSD = 1.5%, n = 6)。结论:所建标准适用于香砂脘痛胶囊的质量控制。

Abstract: Objective: To establish the quality standard Xiangshawantong Capsule. Methods: Thin-Layer chro- matography (TLC) was employed for the qualitative determination of Chuanxiong Rhizoma, Angelicae Sinensis Radix and Paeoniae Radix Rubra High performance liquid chromatography (HPLC) was applied for the determination of Vitexin in Xiangshawantong Capsule. Results: The characteristic by TLC was obvious and highly specific. The Linear range of Vitexin ranged from 0.0576 - 0.2880 μg (r = 0.9998). The average recovery was 99.73% (RSD = 2.1%, n = 6) respectively. Conclusion: The established standard can be used for the quality control of Xiangshawantong Capsule.

文章引用: 辛振杰 , 饶秋红 (2017) 香砂脘痛胶囊质量研究。 药物资讯, 6, 25-30. doi: 10.12677/PI.2017.62005

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