Dominated by Professional Nurse Nutritional Intervention in Patients with Terminal Gastrointestinal Tumor Chemotherapy: An Integrative Research
Abstract: Objective: To evaluate the effect of nutritional improvement in colorectal cancer patients with chemotherapy after nutritional therapy leading by specialized nurse teams. Methods: 248 colo-rectal cancer patients (NRS 2002 score is more than or equal to 3 points) with chemotherapy of The Third Affiliated Hospital of Sun Yat-sen University form January 1st 2014 to June 30th 2015 were collected. The patients were randomly divided into intervention group (30 patients) and the control group (30 patients). The intervention group received personalized recipe which was developed by a team containing professional nurses, chief psychiatrist, family members and patients themselves. The control group was treated with a normal diet guidance. The change about nutrition index of different time and their nutrition improved difference contrast before and after the treatment, and statistical analysis was made when p was less than 0.05. Results: The two groups with 30 patients in each group. The serum albumin and the preprotein improved after 5 months of chemotherapy than before chemotherapy in intervention group (p < 0.05). The D-value of the serum albumin and the preprotein before chemotherapy and 5 months after chemotherapy were improved more significantly in intervention group than the control group (p < 0.05). Conclusion: There is a significant nutritional improvement in colorectal cancer patients with chemotherapy after nutritional therapy leading by specialized nurse teams, which is worthy of application.
文章引用: 林金香 , 方蘅英 (2016) 以专科护士为主导的营养干预对晚期胃肠道肿瘤化疗患者营养改善研究。 护理学， 5， 75-80. doi: 10.12677/NS.2016.54015
 李国立, 李宁, 黎介寿. 从癌的本质看荷瘤病人的营养支持[J]. 中国实用外科杂志, 2006, 26(3): 343-345.
 王晓杰, 郭增清, 范南峰. 营养支持辅助化疗在28例晚期胃癌中的应用. 福建医药杂志, 2009, 31(6): 14-16.
 Pyrhonen, S., Kuitunen, T., Nyandoto, P., et al. (1995) Randomised Comparison of Fluorouracil Epidoxorubicin and Methotrexate (FEMTX) plus Supportive Care with Supportive Care Alone in Patients with Non-Resect Able Gastric Cancer. British Journal of Cancer, 71, 587-591. http://dx.doi.org/10.1038/bjc.1995.114
 Murad, A.M., Santiago, F.F., Petroianu, A., et al. (1993) Modified Therapy with 5-Fluorouracil, Doxorubicin, and Methotrexate in Advanced Gastric Cancer. Cancer, 72, 37-41. http://dx.doi.org/10.1002/1097-0142(19930701)72:1<37::AID-CNCR2820720109>3.0.CO;2-P
 Schipper, D.L. and Wagener, D.J. (1996) Chemotherapy of Gastric Cancer. Anticancer Drugs, 7, 137-149.
 Glimelius, B., Ekstrom, K., Hoffman, K., et al. (1997) Randomized Comparison between Chemotherapy plus Best Supportive Care with Best Supportive Care in Advanced Gastric Cancer. Annals of Oncology, 8, 163-168. http://dx.doi.org/10.1023/A:1008243606668
 Kondrup, J., Rasmussen, H.H., Hamberg, O., et al. (2003) Nutritional Risk Screening (NRS2002): A New Method Based on an Analysis of Controlled Clinical Trials. Clinical Nutrition, 22, 321-336. http://dx.doi.org/10.1016/S0261-5614(02)00214-5
 李宁. 重视肿瘤综合治疗中营养支持的作用[J]. 中国实用外科杂志, 2002, 22(11): 641-644.
 陈双, 吴一冲. 肿瘤病人的营养支持[J]. 中国实用外科杂志, 2003, 23(2): 73-75.
 Sobotka, L. 临床营养基础[M]. 蔡威, 译. 第2版. 上海: 复旦大学出版社, 2002: 18.