The Relationship between CMBs and Different Types of Stroke
Abstract: Purpose: To research the relationship between CMBS and the different types of stroke according to the distribution of CMBS among the history of strokes. Methods: 796 cases from 2010.5-2014.9 were collected in this group, including multiage lacunar infarction, massive cerebral infarction and cerebral hemorrhage. Stroke, according to the 4th CMA national cerebral meeting, include multiage lacunar infarction, massive cerebral infarction and cerebral hemorrhage. Whereas CMBs, according to the standards of conferences, appear as low density lesion small than 5 mm, and exclude cavernous hemangioma, venues, calcification, and diffuse axonal injury. The age, gender, type, number and distribution of stroke of patients were observed and recorded. The extent of stroke includes 3 degrees (mile, 1 - 5 lesions; moderate, 6 - 15 lesions; severe, more than 16 lesions). Methods of examinations include MRI, DWI and SWI (slice thickness 6 mm, interval 7 mm, TR = 50 ms, TE = 40 ms) on all patients with Siemens 1.5 T MRI system. Results: 796 cases were collected in this group, including 481 male cases and 315 female cases, aging from 40 - 80 years with an average of 61.9 years. Their history of hypertension is varying from 0 to 30 years with an average of 12.6 years. 107 cases (about 14.69%) underwent a stroke history more than 2 times; 42 cases were cerebral hemorrhage with 22 CMBS (52.38%); 252 cases were complex cases (infarction and hemorrhage and lacunar infarction) with 84 CMBS (about 33.33%); 98 cases were infarction with 29 CMBS (about 29.59%); 53 cases were hemorrhagic cerebral infarction with 10 CMBs (18.86%); and lacunar infarction were the biggest group, which include 351 cases with 39 CMBs (11.11%). 1399 CMBs were observed in 184 patients, which appears as single lesion, local multi-lesions or global multi-lesions. Among the three degrees, the “moderate” has the largest number, about 51% of the total cases, and mostly distributed in the DGM area. The number in DGM area (1530) was more than those in CSC area (600) and IA area (570). Conclusion: There was an apparent difference of CMBs’ numbers between the different types of stroke, the major group is hemorrhagic cerebral stroke and the major distribution is in the DGM area.
文章引用: 郭兴华 , 张崇杰 , 王俊波 (2016) 微出血与不同类型脑卒中的关系。 医学诊断， 6， 68-72. doi: 10.12677/MD.2016.63012
Gregoire, S.M., Chaudhary, U.J., Brown, M.M., et al. (2009) The Microbleed Anatomical Rating Scale (MARS): Reliability of a Tool to Map Brain Microbleeds. Neurology, 73, 1759-766.
 陈玲, 张微微, 王国强. 脑微出血研究进展[J]. 中国脑血管病杂志, 2014, 11(9): 500-504.
Andreas, C. and David, J.W. (2011) Cerebral Microbleeds: Detection, Mechanisms and Clinical Chal-lenges. Future Neurology, 6, 587-611.
 张持, 王小强, 汪国宏, 等. 脑微出血危险因素的研究进展[J]. 安徽医学, 2013, 34(7): 1032-1033.
Poels, M.M., Vernooij, M.W., Ikram, M.A., et al. (2010) Prevalence and Risk Factors of Cerebral Microbleeds: An Update of the Rotterdam Scan Study. Stroke, 41, S103-S106.
 Roob, G., Lechner, A., Schmidt, R., et al. (2000) Frequency and Location of Cerebral Microbleeds in Patients with Primary Intracerbral Hemorrhage. Stroke, 31, 2665-2669.
Bokura, H., Saika, R., Yamaguchi, T., et al. (2011) Microbleeds Are Associated with Subsequent Hemorrhagic and Ischemic Stroke in Healthy Elderly Individuals. Stroke, 42, 1867-1871.