Effectiveness Observations of Cyclocryotherapy Combined with Trabeculectomy to Neovascular Glaucoma in 25 Cases
Abstract: Objective: To observe the results of cyclocryotherapy combined with trabeculectomy to neovascular glaucoma. Methods: 25 eyes in 25 cases with neovascular glaucoma in the First Affiliated Hospital of Kunming Medical University from Jan. 2012 to Dec. 2014 were analyzed retrospectively. Pan-retina photocoagulations were executed firstly. All patients were treated with intravitreal injection of Lucentis 0.1 ml (1.0 mg) pars plana at first. 3 days latter, 25 eyes were treated by cyclocryostherapy combined with trabeculectomy. Pre- and post-operative (1 week, 1 month, 3 months, 6 months) swelling pain of eye, intraocular pressures (I0P), visual acuity and complications were observed. Results: All the swelling pain of the eye disappeared. The average IOP reduced greatly. The IOP decreased 22.64 mmHg, 23.6 mmHg, 24.2 mmHg, 26.16 mmHg in 1 week, 1 month, 3 months and 6 months in post-operation, respectively. The difference was statistically significant (P < 0.001). After operations, intraocular hypotension in 1 case, shallow anterior chamber in 1 case, anterior chamber hemorrhage in 8 cases, and eyeball atrophy in 3 cases were observed, respectively. 2 eyes were enucleated lastly. Conclusions: Cyclocryotherapy combined with trabeculectomy should be a good method for controlling neovascular glaucoma.
文章引用: 李国栋 , 文雪薇 , 游志鹏 (2016) 睫状体冷凝联合小梁切除术治疗新生血管性青光眼25例疗效观察。 眼科学， 5， 58-63. doi: 10.12677/HJO.2016.53010
Zhou, M.W., Xu, X., Zhang, X.L., et al. (2016) Clinical Outcomes of Ahmed Glaucoma Valve Implantation with or without Intravitreal Bevacizumab Pretreatment for Neovascular Glaucoma: A Systematic Review and Meta-Analysis. Journal of Glaucoma, 25, 551-557.
 金怡轩, 张少冲. 新生血管性青光眼的治疗动态[J]. 国际眼科纵览, 2009, 33(5): 327-331.
 赵怡红. 新生血管性青光眼治疗分析[J]. 中国实用眼科杂志, 2003, 21(5): 349.
 景晓彬, 赵智慧, 赵春梅, 等. 综合手术与单纯睫状体冷冻治疗新生血管性青光眼疗效观察[J]. 中国实用眼科杂志, 2005, 6(23): 591-592.
Kitnarong, N., Sriyakul, C. and Chinwattanakul, S. (2015) A Prospective Study to Evaluate Intravitreous Ranibizumab as Adjunctive Treatment for Trabeculectomy in Neovascular Glaucoma. Ophthalmology and Therapy, 4, 223-225.
 孙重, 吴作红. 眼引流阀治疗新生血管性青光眼的临床疗效[J]. 国际眼科杂志, 2014, 14(2): 243-245.
 Macarie, S. and Palko, Z. (2006) Therapeutical Difficulties in Neovascu1ar Glaucoma. Oph-thalmologia, 50, 73-76.
 王千. 两种手术方法治疗绝对期新生血管性青光眼的疗效对比[J] .国际眼科杂志, 2014, 14(9): 1638-1640.