均相沉积法制备磁性羟基磷灰石
Fabrication of Magnetic Hydroxyapatite by a Homogeneous Precipitation Method

作者: 闫 艳 , 张 熠 , 左 奕 , 李玉宝 , 李吉东 :四川大学分析测试中心,纳米生物材料研究中心,四川 成都;

关键词: 羟基磷灰石四氧化三铁磁性柠檬酸铵Hydroxyapatite Ferroferric Oxide Magnetism Ammonium Citrate

摘要:
本文将Fe3O4纳米颗粒分散在Ca、P溶液中,通过尿素酶催化水解尿素提高Ca、P溶液PH值,以纳米Fe3O4为成核位点,通过均相沉积法制备具有核–壳结构的Fe3O4/HA磁性复合物。通过X射线衍射(XRD)、透射电镜(TEM)、扫描电镜(SEM)等分析手段分析探讨了Ca/P摩尔比和分散剂柠檬酸铵用量对磁性羟基磷灰石复合颗粒组成、结构和颗粒尺寸的影响。结果表明当溶液中Ca/P摩尔比为5:3,分散剂柠檬酸铵用量为1.5~3.0 g/500ml,Fe3O4磁性粒子基本完全被沉积的羟基磷灰石包覆,可制得颗粒尺寸较小的球状核壳结构磁性Fe3O4/HA复合物。

Abstract: A core-shell nano-iron oxide/hydroxyapatite (Fe3O4/HA) composite was synthesized by using a homogeneous precipitation method. Fe3O4 nano-particles synthesized by chemical precipitation were dispersed and used as substrate in Ca, P solution to deposit HA on the Fe3O4 spheres through slowly increase of pH by decomposition of urea using urease as the catalytic. The influence of Ca/P molar ratio and varying dosages of dispersing agent (ammonium citrate) on the composition, structure and particle diameter of fabricated Fe3O4/HA was investigated. The obtained samples were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and scan-ning electron microscopy (SEM). The results showed that a spherical core-shell Fe3O4/HA composite with magnetic properties, and smaller particle size were obtained under Ca/P molar ratio of 5:3 and ammonium citrate concentration of 1.5 - 3.0 g/500ml.

文章引用: 闫 艳 , 张 熠 , 左 奕 , 李玉宝 , 李吉东 (2016) 均相沉积法制备磁性羟基磷灰石。 材料科学, 6, 223-229. doi: 10.12677/MS.2016.64028

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