龙葵素抗肿瘤作用研究进展
Progress of Anti-Cancer Function of Solanine

作者: 李兰香 , 杨 青 :湖南农业大学动物医学院,湖南 长沙 ; 熊兴耀 :中国农业科学院蔬菜花卉所,北京;湖南省作物种质创新与资源利用重点实验室,湖南 长沙;

关键词: 糖苷生物碱龙葵素抗肿瘤细胞凋亡Glycoalkaloids Solanine Anti-Cancer Apoptosis

摘要:
龙葵素是一种重要的糖苷生物碱,具有多种生物学作用,能对多种疾病起到防治的作用,其中包括抗肿瘤作用。龙葵素在抗肿瘤作用从细胞和分子途径诱导细胞的凋亡和自噬,使癌细胞的迁移、浸润、血管发生一起转移能力受到抑制。因此,本文就龙葵素对各种癌细胞的抑制作用及其作用机制进行了综述。

Abstract: Solanine is an important glycoalkaloid, with a variety of biological effects. It plays a role in pre-vention and treatment of many diseases, including its anti-tumor effect. Solanine exhibits its an-ti-tumor effect through regulation several cellular and molecular pathways which induce cell apoptosis and autophagy, and inhibit cancer cells’ migration, invasion, angiogenesis and metastasis. Therefore, anti-cancer effects of solanine and its mechanism are reviewed in this article.

文章引用: 李兰香 , 熊兴耀 , 杨 青 (2016) 龙葵素抗肿瘤作用研究进展。 食品与营养科学, 5, 26-30. doi: 10.12677/HJFNS.2016.52004

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