Chinical Study of Immune Reconstitution Retinopathy
关键词: AIDS； HAART； 免疫重建性综合征； 巨细胞性视网膜炎； Acquired Immunodeficiency Syndrome (AIDS)； Highly Active Antiretroviral Therapy (HAART)； Immune Reconstitution Inflammatory Syndrome (IRIS)； Cytomegalovirus Retinitis摘要:
Abstract: Purpose: To determine the clinical features of immune reconstitution retinopathy among HIV-in- fected individuals which were receiving highly active antiretroviral therapy (HAART). Methods: 26 HIV-infected patients who were diagnosed in our department of infectious diseases were chosen. The clinical data of the patients with immune reconstitution retinopathy initiated by highly active antiretroviral therapy (HAART) were retrospectively reviewed. Results: In our series of 26 patients, all patients presented with decreased visual acuity. The most common ocular manifestation was cytomegalovirus retinitis with fundus findings of wide-whitened retina, granular margin, extensive hemorrhage and exudations. All cases were accompanied by panuveitis. Conclusions: Immune reconstitution inflammatory syndrome (IRIS) is a complication caused by reactivation of the immune system that can occur after starting highly active antiretroviral therapy (HAART). Im-proving the ability of identification of IRIS is the most important way to reduce the delays in diag-nosis and treatment.
文章引用: 张晓湄 , 欧穗珍 , 沈 念 (2016) 免疫重建性视网膜病变的临床研究。 眼科学， 5， 18-21. doi: 10.12677/HJO.2016.51004
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