Study on the Diagnostic Value of Myocardial Perfusion Imaging in Coronary Artery Disease (CAD)

作者: 包秋胜 , 张轶群 :内蒙古医科大学,内蒙古 呼和浩特;

关键词: 冠心病核素心肌灌注显象冠状动脉造影冠状动脉钙化积分CAD MPI Coronary Arteriography Coronary Artery Calcification Score


Abstract: As the increasingly improved quality of people’s life, coronary artery disease (CAD) has become one of the most dangerous cardiovascular diseases that threat against people’s health and life, the mankind’s first killer in the world. Myocardial Perfusion Imaging (MPI) is the most common diag-nosis method used in non-trauma-examination on CAD. MPI can pre-judge the degree and the range of Coronary Artery Disease, also give an accurate medical assessment on myocardial ischemia. As the development and mature technology use of MPI these years, there have been massive clinical data home and abroad about it in CAD risk grading, prevention, treatment protocols and prognostic evaluation. This review is to summarize the comprehensive information about MPI, giving reference in its clinical application.

文章引用: 包秋胜 , 张轶群 (2016) 核素心肌灌注显像对冠心病的诊断价值。 临床医学进展, 6, 50-54. doi: 10.12677/ACM.2016.61010


[1] 齐惠英, 郑刚. 存活心肌无创性检查的现状[J]. 医学综述, 2008, 14(24): 3747-3749.

[2] 刘征, 关世奎, 王宏伟, 等. 放射性核素显像在评估存活心肌中的应用[J]. 标记免疫分析与临床, 2015, 22(3): 250-253.

[3] Weustink, A.C. and de Feyter, P. (2011) The Role of Multi-Slice Computed Tomography Instable Angina Management: A Current Perspective. Netherlands Heart Journal, 19, 336-343.

[4] Hongwei, S., Jianhua, G. and Shengzu, C. (2007) Nuclear Medicine Scans in Beijing: Insights from the Beijing Quality Control Centre Survey 2005-2006. Nuclear Medicine Communications, 28, 661-666.

[5] Berman, D.S., Hachamovitch, R., Shaw, L.J., Friedman, J.D., Hayes, S.W., Thomson, L.E., et al. (2006) Roles of Nuclear Cardiology, Cardiac Computed Tomography, and Cardiac Magnetic Resonance: Assessment of Patients with Suspected Coronary Artery Disease. Journal of Nuclear Medicine, 47, 74-82.

[6] Mollet, M.R., Cademartiri, F., Van Mieghem, C.A., et al. (2005) High-Resolution Spiral Computed Tomography Coronary Angiography in Patients Referred for Diagnosic Conventional Coronary Angiography. Circulation, 112, 2318- 2323.

[7] Shaw, L.J., Shaw, R.E., Merz, C.N., et al. (2008) Impact of Ethnicity and Gender Differences on Angiographic Coronary Artery Disease Prevalence and In-Hospital Mortality in the American College of Cardiology-National Cardiovascular Data Registry. Circulation, 117, 1787-1801.

[8] Wennberg, D.E., Kellett, M.A., Dickensjd, J.D., et al. (1996) The Association between Local Diagnostic Testing Intensity and Invasive Cardiac Procedures. JAMA, 275, 1161-1164.

[9] Schuijf, J.D., Wijns, W., Jukema, J.W., et al. (2006) Relationship between Noninvasive Coronary Angiography with Mufti-Slice Computed Tomography and Myocardial Perfusion Imaging. Journal of the American College of Cardiology, 48, 2508-2514.

[10] Gibbons, R.J., Abrams, J., Chatterjee, K., et al. (2003) ACC/AHA 2002 Guideline Update for the Management of Patients with Chronic Stable Angina-Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Committee on the Management of Patients with Chronic Stable Angina). Circulation, 107, 149-158.

[11] 黄艳玲, 赵颖, 牛晓楠. 核素心肌灌注显像与冠状动脉造影的对比分析[J]. 临床影像技术, 2010, 25(10): 139-140.

[12] 朱红静, 赵亮, 刘俊才. 负荷核素心肌灌注断层显像与冠状动脉造影在冠心病诊断中的价值对比[J]. 临床医药文献杂志, 2015, 2(14): 2859-2860.

[13] Klocke, F.J., Baird, M.G., Lorell, B.H., Bateman, T.M., Messer, J.V., Berman, D.S., et al. (2003) ACC/AHA/ASNC Guidelines for the Clinical Use of Cardiac Radionuclide Imaging—Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Cardiac Radionuciide Imaging). Circulation, 108, 1404-1418.

[14] Lexanderson, E., Jacome, R., Romero, E., et al. (2011) The Importance of Multi-Imaging Diagnosis in Cardiology. Archivos Del Instituto de Cardiologia de Mexico, 81, 154-157.

[15] 侯凤丽. 核素心肌灌注显像对缺血性心脏病的诊断作用[J]. 微循环学杂志, 2014, 24(2): 77-79.

[16] Nallamothu, N., Pancholy, S.B., Lee, K.R., Heo, J. and Iskandrian, A.S. (1995) Impact on Exercise Sin-gle-Photon Emission Computed Tomographic Thallium Imaging on Patient Management and Outcome. Journal of Nuclear Cardiology, 2, 334-338.

[17] Miller, T.D., Hodge, D.O., Milavetz, J.J. and Gibbons, R.J. (2007) A Normal Stress SPECT Scan Is an Effective Gatekeeper for Coronary Angiography. Journal of Nuclear Cardiology, 14, 187-193.

[18] Brown, K.A., Altland, E. and Rowen, M. (1994) Prognostic Value of Normal Technetium-99m-Sestamibi Cardiac Imaging. Journal of Nuclear Medicine, 35, 554-557.

[19] 林振宇, 李殿富. 核素心肌灌注显像在冠心病中的应用进展[J]. 心血管病学进展, 2013, 34(5): 626-630.

[20] Arad, Y., Goodman, K.J., Roth, M., et al. (2005) Coronary Calcification, Coronary Disease Risk Factors, c-Reactive protein, and ath-Erosclerotic Cardiovascular Disease Events: The St. Francis Heart Study. Journal of the American College of Car-diology, 46, 158-165.

[21] 汤喆, 白静, 王禹. 冠状动脉钙化[J]. 中华心血管病杂志, 2013, 41(10): 900-902.

[22] Budoff, M.J. and Gul, K.M. (2008) Expert Review on Coronary Calcium. Vascular Health and Risk Management, 4, 315-324.

[23] Hecht, H.S., Budoff, M.J., Berman, D.S., et al. (2006) Coronaryartery Calcium Scan-ning: Clinical Paradigms for Cardiac Risk Assessment and Treatment. American Heart Journal, 151, 1139-1146.

[24] 邵燕惠, 钱农, 薛跃君. 螺旋CT冠状动脉钙化积分与冠状动脉造影对比分析[J]. 实用医技杂志, 2007, 14(9): 1105-1107.

[25] Gaemperli, O., Schepis, T., Valenta, I., et al. (2007) Cardiac Image Fusion from Stand-Alone SPECT and CT: Clinical Experience. The Journal of Nuclear Medicine, 48, 696-703.

[26] Tiziano, S., Oliver, G., Pascal, K., et al. (2007) Added Value of Coronary Artery Calcium Score as an Adjunct to Gated SPECT for the Evaluation of Coronary Artery Disease in an Intermediate-Risk Population. Journal of Nuclear Medicine, 48, 1424-1430.

[27] 张雷, 张追阳, 倪建明, 等. 冠状动脉钙化积分在SPECT/CT核素心肌灌注显像中的应用价值探讨[J]. 南京医科大学学报, 2015, 35(5): 702-705.

[28] 巴雅, 秦永德, 刘文亚, 等. CT冠脉钙化积分与核素心肌显像的相关性分析[J]. 新疆医科大学学报, 2010, 33(12): 1446-1449.

[29] Feldman, C., Vitola, D. and Schiava, N. (2000) Detection of Coronary Artery Disease Based on the Calcification Index Obtained by Helical Computed Tomography. Arquivos Brasileiros de Cardiologia, 75, 471-480.