Protective Effect of Nitric Oxide and Natural Antioxidants on Stability of Blood Vessel
Abstract: The protective effects of a formula of nitric oxide and natural antioxidants on increases of blood lipid, and glucose of kkay mouse and blood pressure of rat caused by higher lipid food were studied. It was found that higher lipid food and gene caused significant increase body weight, liver weight and blood lipid and blood glucose of kkay mouse, while the formula of nitric oxide and natural antioxidants could decrease the increases of body weight (about 9% and 12.5% for low and high doses respectively), liver weight/body weight (about 17.8% and 20.2% for low and high doses respectively), cholesterol (about 11.0% and 15.6% for low and high doses respectively), triglyceride (about 29.8% and 35.5% for low and high doses respectively), low density lipid protein (about 24.6% and 25.4% for low and high doses respectively), however increase the high density lipid protein (about4.8% and 18.9% for low and high doses respectively). The formula also could decrease the increases of fasting blood glucose (about 36.2% and 44.1% for low and high doses respectively), random blood glucose (about 47.6% and 56.7% for low and high doses respectively) and 2-hour blood glucose (about 33.1% and 44.1% for low and high doses respectively). It was also found that higher lipid food caused significant increase of blood pressure of rats about 73% and that the formula could decrease the blood pressure about 12% and 18% for low and high doses respectively. Further study found that the formula could scavenge hydroxyl and superoxide free radicals. It suggests that the formula of nitric oxide and natural antioxidants can protect blood vessel against the damage caused by higher lipid food and genetic factors through scavenging oxygen free radicals.
文章引用: 高明景 , 张俊静 , 赵保路 (2016) 一氧化氮和天然抗氧化剂对血管稳定性的调节和保护作用。 食品与营养科学， 5， 1-11. doi: 10.12677/HJFNS.2016.51001
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