Clinical Research on the Turbidity Relief Formula in the Treatment of Nonalcoholic Fatty Liver Disease
Abstract: Objective: To investigate the clinical efficacy and therapeutic mechanism of turbidity relief Formula on nonalcoholic steatohepatitis (NASH). Methods: Two hundred patients who were diagnosed as NASH according to nonalcoholic fatty liver disease diagnosis guideline and turbid phlegm and blood stasis types were randomly divided into the turbidity relief Formula group (100) and control group (100). The turbidity relief Formula group was given turbidity relief Formula, while the control group was given N-(2-Mercaptopropionyl) glycine Capsule. Both of the two groups’ courses of treatment were 8 weeks. The changes of alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyltransferase (GGT), cholesterol total (TC), triglyceride (TG) levels, brightness-mode ultrasound of liver and the CT of the epigastrium were observed and compared. Results: The total effective rates of the turbidity relief Formula group and the control group were respectively 94% and 75% by Ridit method analyzed (P < 0.05). The levels of ALT, AST, GGT, TC and TG were decreased significantly after the treatment in both groups (P < 0.05) and the comparative difference between groups was statistically significant (P < 0.05). Conclusion: The turbidity relief formula in the treatment of the turbid phlegm and blood stasis type in NASH can ameliorate the clinical symptoms of, improve the liver function and reduce the blood lipids, and has a good effect on NASH. The total effective rate was 94%.
文章引用: 王邦才 , 王玲玲 , 袁建芬 , 朱奇雄 , 潘东梅 , 王培劼 , 王 杰 , 王 益 (2016) 泄浊化瘀方治疗非酒精性脂肪性肝炎的临床研究。 中医学， 5， 30-35. doi: 10.12677/TCM.2016.51006
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