包头地区结直肠癌发病风险因素的病例对照研究
The Risk Factors of Colorectal Cancer in Baotou: A Case-Control Study

作者: 张树春 , 白 涛 :包头市中心医院肿瘤外科,内蒙古 包头;

关键词: 结直肠癌发病风险病例对照Colorectal Cancer Risk Factors Case-Control Study

摘要:
目的:研究影响结直肠癌发病的风险因素,为预防和控制结直肠癌的发病提供理论基础。方法:本次研究采用病例对照研究的方法,回顾性收集在我院住院的90例结直肠癌患者作为病例组,并选取同期住院的90例非肿瘤患者作为对照组,收集相关资料,研究影响结直肠癌发生的危险因素。结果:单因素分析发现,高脂肪饮食(OR = 2.28, 95%CI: 1.13~3.91)、食用新鲜蔬菜少(OR = 3.66, 95%CI: 1.93~6.78)、体育锻炼少(OR = 2.22, 95%CI: 1.09~3.81)、饮酒(OR = 1.99, 95%CI: 0.89~3.12)、文化程度低(OR = 3.50, 95%CI: 1.90~6.61)、恶性肿瘤家族史(OR = 2.60, 95%CI: 1.09~6.49)、阑尾炎史(OR = 3.98, 95%CI: 1.70~10.89)是结直肠癌发病的风险因素;多元Logistic回归模型进行分析发现,食用新鲜蔬菜少(OR = 1.732, 95%CI: 0.812~2.944)、文化程度低(OR = 1.885, 95%CI: 1.447~3.996)、阑尾炎史(OR = 1.495, 95%CI: 0.994~3.231)是结直肠癌发病的独立危险因素。结论:食用新鲜蔬菜少、低文化程度、有阑尾炎史的人群是结直肠癌高发的人群,针对这类重点人群需要加强预防和干预。

Abstract: Objective: To study the risk factors of colorectal cancer and provide the basis to prevent and control the disease. Methods: The case-control study was used. The information of 90 cases of colorectal cancer patients in our hospital was retrospectively collected as the case group and 90 cases of non-hospitalized cancer patients in the corresponding period was selected as the control group. Results: Univariate analysis showed that high fat diet (OR = 2.28, 95%CI: 1.13 - 3.91), less eating fresh vegetables (OR = 3.66, 95%CI: 1.93 - 6.78), less physical exercise (OR = 2.22, 95%CI: 1.09 - 3.81), drinking wine (OR = 1.99, 95%CI: 0.89 - 3.12), low educational level (OR = 3.50, 95%CI: 1.90 - 6.61), family history of cancer (OR = 2.60, 95%CI: 1.09 - 6.49) and history of appendicitis (OR = 3.98, 95%CI: 1.70 - 10.89) were risk factors for the colorectal cancer. Multiple Logistic regression analysis found that less eating fresh vegetables (OR = 1.732, 95%CI: 0.812 - 2.944), low educational level (OR = 1.885, 95%CI: 1.447 - 3.996) and history of appendicitis (OR = 1.495, 95%CI: 0.994 - 3.231) were independent risk factors for the colorectal cancer. Conclusion: The populations with less eating fresh vegetables, low education level and the history of appendicitis are the high risk people and it is necessary to strengthen the prevention and intervention.

文章引用: 张树春 , 白 涛 (2015) 包头地区结直肠癌发病风险因素的病例对照研究。 亚洲肿瘤科病例研究, 4, 27-31. doi: 10.12677/ACRPO.2015.44005

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