Injection of Triamcinolone Acetonide (TA) under Tenon’s on the Macular Serous Retinal Detachment of Vogt-Koyanagi-Harada (VKH) Disease
Abstract: Objectives: To observe the clinic effect of Vogt-Koyanagi- Harada (VKH) Disease by injecting triamcinolone acetonide (TA) under Tenon’s. Methods: 34 eyes of 18 consecutive patients diagnosed with acute Vogt-Koyanagi-Harada Disease by FFA and OCT. All the patients were given pmethylprednisolone combined with triamcinolone acetonide (TA) injection under Tenon’s, and the frequency is once a month, 20 mg/0.5ml every time, and it will be done totally three times. All the patients were performed no-corrected visual activity, best corrected visual activity, slit- lamp check, fundus photograph and spectral-domain optical coherence tomography (OCT) at the initial visit and 6 months after steroid treatment. All the data were analyzed by SPSS 17.0. Results: After the treatment, all the patients’ VA improved. At the initial, all eyes showed the most hyperfluorescence pinpoints and the leakage of fluorescence pooling. After treatment for 6 months, the FFA of 32 patients showed normal. The thickness of fovea was (378 ± 234) μm before treatment and (153 ± 67) μm after treatment, which decreased by 59.5% on average; there was significantly difference between the two groups (p < 0.01). Conclusion: For VHK disease, the treatment of pmethylprednisolone combined with TA injection under Tenon’s can improve the macular serous retinal detachment and reduce the relapse of the disease.
文章引用: 肖 静 , 高付林 , 郭惠玲 (2015) 曲安奈德后Tenon囊下注射治疗Vogt-小柳-原田氏病黄斑部浆液性脱离。 眼科学， 4， 47-51. doi: 10.12677/HJO.2015.43009
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