A Case of Breast Intraductal Papilloma in Tree Shrews (Tupaia belangeri chinensis)
Abstract: A case of breast intraductal papilloma of tree shrews is described. Masses in the breast area were found in a 3-year-old female tree shrew. The lump diameter is about 1 cm, irregular oval and smooth surface. Histopathological examination with H.E staining showed that mass contained breast specific terminal ductal structures and a small amount of breast lobules, which was composed of ductal papillary and lobular hyperplasia. The nipple was less branching and more bulky; the cell volume was bigger; the cell boundary was clear; the nuclear division was rare, and accompanied by sweat gland metaplasia. The nucleus is located in the side of the cell, and the cytoplasm is rich and red with necrosis. The pathological feature of case supported the diagnosis of breast intraductal papilloma.
文章引用: 匡德宣 , 孙晓梅 , 王文广 , 陆彩霞 , 罕园园 , 仝品芬 , 代解杰 (2015) 树鼩乳腺导管内乳头状瘤一例。 亚洲兽医病例研究， 4， 26-29. doi: 10.12677/ACRPVM.2015.43005
 刘彤华 (1994) 诊断病理学. 人民卫生出版社, 北京, 574-576.
Fan, Y., Huang, Z.Y., Cao, C.C., et al. (2013) Genome of the Chinese tree shrew. Nature Communications, 4, 1426- 1434.
 许凌, 范宇, 蒋学龙, 等 (2013) 树鼩进化分类地位的分子证据. 动物学研究, 2, 70-76.
 苏傲蕾, 秦银鸽, 郑禹, 等 (2014) 树鼩的生物学特性研究概述. 动物医学进展, 10, 115-118.
 何保丽, 杨仁华, 李进涛, 等 (2013) 树鼩自发性乳腺癌的病理学观察. 动物医学进展, 11, 135-136.
 夏厚军, 王春艳, 张海林, 等 (2012) 自发性树鼩乳腺肿瘤的特性. 动物学研究, 1, 55-59.
Elliot, O.S., Elliot, M.W. and Lisco, H. (1966) Breast cancer in a tree shrew (Tupaia glis). Nature, 211, 1105.
 Darai, G., Zöller, L., Hofmann, W., et al. (1982) Spontaneous ma-lignomas in Tupaia (tree shrew). American Journal of Primatology, 2, 177-189.
Brack, M. (1988) Malignant leydig cell tumour in a Tupaia belangeri: Case report and literature review of male genital tumours in non-human primates. Laboratory Animals, 2, 131-134.
 徐小珊, 侯小明, 王伟, 等 (2015) DMBA诱导树鼩乳腺肿瘤(中缅树鼩). 现代生物医学进展, 2, 228-232.