乙肝病毒cccDNA的研究现状
The Research Status of Hepatitis B Virus cccDNA

作者: 王 宁 :贵州省道真县扶贫开发办公室,贵州 遵义;

关键词: 乙型肝炎病毒松弛环状双链DNA共价闭合环状DNAHBV rcDNA cccDNA

摘要: 乙型肝炎病毒(HBV)是一种小DNA病毒,共价闭合环状DNA (cccDNA)是HBV的原始复制模板,对乙肝病毒的复制及感染状态的建立具有重要意义。本文旨在对近年来有关cccDNA的形成、常用检测方法、抗病毒药物对其的影响等方面的进展作一综述报道。

Abstract: The hepatitis B virus (HBV) is a kind of small DNA virus. The original template of covalently closed circular DNA (cccDNA) HBV is very important for the replication of the hepatitis B virus and the establishment of infection status. The progress of the formation of cccDNA, the methods of detection and the impact of antiviral drugs were reviewed in this paper.

文章引用: 王 宁 (2015) 乙肝病毒cccDNA的研究现状。 免疫学研究, 3, 13-18. doi: 10.12677/IS.2015.32002

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