长期被误诊的2例乳房外Paget病
Two Case Report of Extramammary Paget’s Disease Being Long-Term Misdiagnosed

作者: 贾亚利 , 刘 珏 , 蔡莺莲 :杭州市第一人民医院皮肤科,浙江 杭州; 谢乐斯 :杭州市第一人民医院病理科,浙江 杭州;

关键词: Paget病误诊Paget’s Disease Misdiagnosis

摘要:
乳房外Paget病是一种罕见的,起源于顶泌汗腺导管开口的恶性肿瘤。表现为有顶泌汗腺部位的皮肤边界清楚的慢性浸润性红色斑块,多发生于外生殖器、腋窝、肚脐等部位,红斑瘙痒是最常见的症状,也可以出现糜烂、渗出、结痂等,临床表现的多样性,导致会经常出现误诊,在一定程度上耽误治疗。本文介绍了2例被误诊的乳房外Paget病,分析了相关的原因。

Abstract: Extramammary Paget’s disease (EMPD) is a rare cutaneous adenocarcinoma and usually originates from the duct openings of apocrine sweat glands. The disease appears as a well-defined chronically infiltrated plaque in the skin with apocrine sweat glands. The genitalia, armpits and navel are most commonly affected. While pruritic erythematous plaque is the most common symptom, erosion, oozing, crusting could also be observed. The diversity of the clinical manifestations sometimes leads to misdiagnosis, even delayed treatment. Two cases of misdiagnosed EMPD and the possible reasons for the misdiagnosis are discussed in this article.

文章引用: 贾亚利 , 刘 珏 , 谢乐斯 , 蔡莺莲 (2015) 长期被误诊的2例乳房外Paget病。 医学诊断, 5, 17-20. doi: 10.12677/MD.2015.52004

参考文献

[1] 朱学骏, 王宝玺, 孙建方, 等译 (2014) 皮肤病学. 第二版, 北京大学医学出版社, 北京, 1323-1328.

[2] Wang, Z., Lu, M., Dong, G., et al. (2008) Penile and scrotal Paget’s disease: Experience from 130 Chinese patients with a long-term follow-up. BJU International, 102, 485-488.

[3] 叶兴东, 韩建德, 罗育武, 等 (2006) 误诊6年的乳房外Paget病2例报道. 中国中西医结合杂志, 1, 15-17.

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