The Measurement and Analysis of Posterior Choroidal Thickness in 100 Medical Students
Abstract: Objective: To study posterior choroidal thickness in 100 medical students and to determine its cor-relation with sex and axial length. Materials and Methods: Cross-sectional observational study of 197 eyes in 100 medical students (mean age = 23.1 ± 1.1 years). The macular choroid was imaged using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). Subfoveal choroidal thickness (SFCT) and choroidal thickness were measured by visual inspection and manual fitting of the choroidal borderlines, at 3 mm inferior, superior, nasal, and temporal to the fovea, respectively. Results: The mean SFCT was 202.8 ± 49.0 µm. The choroidal thickness was the biggest (235.9 ± 68.4 µm) at 3 mm superior to the fovea, and was the thinnest (150.5 ± 55.5 µm) at 3 mm nasal to the fovea. No significant difference had been found in the choroidal thickness between male and female volunteer (P > 0.05), either between right and left eyes (P > 0.05). Ocular axial length between 23.23 mm to 27.88 mm, foveal nasal lateral choroidal thickness decreased by 17.46 µm per mm along axial length, the difference between the other four sites of the choroidal thickness was without obvious regularity. Conclusions: The posterior choroidal thickness of 100 medical students has nothing to do with sex, while the foveal nasal lateral choroidal thickness gets thinner with the axial growth.
文章引用: 刘红霞 , 刘 政 , 王少鹏 , 李凯军 , 李晓琴 , 马丙芬 (2015) 100名医学生后极部脉络膜厚度的测量与分析。 眼科学， 4， 21-26. doi: 10.12677/HJO.2015.42004
 Bron, A.J., Tripathi, R.C., Wolff, E., et al. (1998) Wolff’s anatomy of the eye and orbit. 8th Edition, Chapman & Hall Medical, London.
 Ikuno, Y., Kawaguchi, K., Nouchi, T., et al. (2010) Choroidal thickness in healthy Japanese subjects. Investigative Ophthalmology Visual Science, 51, 2173-2176.
 Margolis, R. and Spaide, R.F. (2009) A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. American Journal of Ophthalmology, 147, 811-815.
 Spaide, R.F., Koizumi, H. and Pozzoni, M.C. (2008) Enhanced depth imaging spectral-domain optical coherence tomography. American Journal of Ophthalmology, 146, 496-500.
 Li, X.Q., Larsen, M. and Munch, I.C. (2011) Subfoveal choroidal thickness in relation to sex and axial length in 93 Danish uni-versity students. Investigative Ophthalmology Visual Science, 52, 8438-8441.
 Hirata, M., Tsujikawa, A., Matsu-moto, A., et al. (2011) Macular choroidal thickness and volume in normal subjects measured by swept-source optical coherence tomography. Investigative Ophthalmology Visual Science, 52, 4971-4978.
 Ding, X., Li, J., Zeng, J., et al. (2011) Choroidal thickness in healthy Chinese subjects. Investigative Ophthalmology Visual Science, 52, 9555-9560.
 Tanabe, H., Ito, Y., Iguchi, Y., et al. (2011) Correlation between cross-sectional shape of choroidal veins and choroidal thickness. Japanese Journal of Ophthalmology, 55, 614-619.
 Usui, S., Ikuno, Y., Akiba, M., et al. (2012) Circadian changes in subfoveal choroidal thickness and the relationship with circulatory factors in healthy subjects. Investigative Ophthalmology Visual Science, 53, 2300-2307.
 Ouyang, Y., Heussen, F.M., Mokwa, N., et al. (2011) Spatial distribution of posterior pole choroidal thickness by spectral domain optical coherence tomography. Investigative Ophthalmology Visual Science, 52, 7019-7026.
 Sogawa, K., Nagaoka, T., Takahashi, A., et al. (2012) Relationship between choroidal thickness and choroidal circulation in healthy young subjects. American Journal of Ophthalmology, 153, 1129-1132.