The Curative Effect of HaierFu Liquid on Alzheimer’s Disease by Aluminum Lead Poisoned Mice
Abstract: Objective: To explore the curative effect of HaierFu liquid on Alzheimer’s disease by aluminum lead poisoned mice. Methods: 48 Kunming white mice were divided into 4 groups: normal group, model group, treated group 1 and treated group 2. There were 12 rats in each group. Mice of the later three groups were fed with AlCl3 and Al(NO3)3 for three months to make aluminum lead poisoned mice model. After being poisoned two months, mice of treated group 1 and treated group 2 were poured with different dosages of Chinese medicine—HaierFu liquid for one month, and mice of normal group and model group were poured with equal pure water at the same time. Blood Hemoglobin (Hb) was determined before and after experiment, and biochemical indices of serum and brain tissue were determined at the end of experiment. Result: The vitality of TchE in brain tissue of model group was obviously lower than that of other groups (P < 0.01 or P < 0.05). However, the content of MDA in brain tissue of model group was obviously higher than that of treated group (P < 0.01 or P < 0.05), and for the clearance rate of oxygen-free radicals, normal group was the highest while model group was the lowest. There was no obvious difference of Hb and Tc in serum, and ALT in serum among each group. Conclusion: The vitality of TchE in brain tissue and the clearance rate of oxygen-free radicals in Alzheimer’s disease by aluminum lead poisoned mice were obviously decreased; HaierFu liquid have an obvious curative effect on Alzheimer’s disease by aluminum lead poisoned mice.
文章引用: 赵凤珍 , 王 娜 , 黄斯梅 , 陆艳梅 , 李 海 , 张树球 , 马 允 , 何 胜 (2014) 海尔福治疗对铝造模阿尔茨海默病小鼠大脑神经损害后再生效果的研究。 老龄化研究， 1， 63-68. doi: 10.12677/AR.2014.14010
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