Research Advances of AMMECR1
Abstract: AMMECR1 (Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis chromo-somal region gene 1) is a gene from the novel X-linked contiguous gene deletion syndrome AMME critical region. It encodes a transcript that is conserved throughout the course of evolution. There is a considerable degree of homology between the AMMECR1 proteins from different species ranging from bacteria and archaea to eukaryotes. This conservation suggests that AMMECR1 and its homologue proteins may exert essential functions in a variety of organisms. In this review, we will describe that AMMECR1 expression, crystal structure, phosphorylation, function-related proteins, miRNAs targeting to AMMECR1 and its interaction partner to promote the study of AMMECR1.
文章引用: 周化民 , 蔡成峰 , 徐 盟 , 李 光 (2015) AMMECR1的研究进展。 生物物理学， 3， 1-6. doi: 10.12677/BIPHY.2015.31001
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