The Progress of Antitumor Interstitial Treatment Strategy of Malignant Ovarian Cancer

作者: 郭振超 , 张天柱 , 顾 宁 :东南大学生物科学与医学工程学院,江苏省生物材料与器件重点实验室,南京;

关键词: 卵巢癌化疗耐药肿瘤间质生存率Ovarian Cancer Chemotherapy Resistance Tumor Interstitium Survival Rate



Abstract: More than 80% of the patients with ovarian cancer chemotherapy relapse due to drug resistance, which makes the highest ovarian cancer mortality rates among the gynecologic malignancies. Compared with the highly heterogeneous tumor cell differentiation, tumor stroma cells have genetic stability, and it is unlikely to produce acquired mutations and lead to drug resistance. In view of the treatment strategies for tumor interstitium, ovarian cancer is reviewed in this paper. At the same time, we pointed out the direction for reducing toxicity, preventing the cancer recurrence and metastasis, improving the survival rate in the treatment of gynecologic malignancies.

文章引用: 郭振超 , 张天柱 , 顾 宁 (2013) 恶性卵巢癌抗肿瘤间质治疗策略研究进展。 亚洲妇产科病例研究, 1, 19-23. doi: 10.12677/ACROG.2013.14005


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