眼压降低后原发性慢性闭角型青光眼角膜中央厚度和视野损害进展的关系
Association between CCT and Visual Field Progression in Patients with Chronic Primary Angle-Closure Glaucoma after IOP Reduction

作者: 刘 青 :上海交通大学医学院附属同仁医院眼科,上海;

关键词: 青光眼慢性闭角型青光眼角膜厚度视野进展Glaucoma Chronic Primary Angle-Closure Glaucoma Central Corneal Thickness Visual Field Progression

摘要:
目的:通过比较中央角膜厚度不同的原发性慢性闭角型青光眼患者在眼压降低后视野是否发生改变探讨中央角膜厚度和慢性闭角型青光眼进展程度之间的关系。方法:44(86)例患者以中央角膜厚度 540 μm<540 μm分为2组,全部患者均行Humphrey静态自动视野(30-2 SITA)检查,随访二年以上,比较眼压降低前后视野平均缺损(MD)改变是否与角膜厚度相关。结果:一组(<540 μmn = 40)MD进展值为0.595 ± 4.578;二组(540 μm, n = 46)MD进展值为0.632 ± 3.37MD进展值比较差异无统计学意义(P = 0.9571)结论:慢性闭角型青光眼患者,眼压降低控制后,不同的角膜厚度,视野无进一步明显进展。

Abstract:
Objective: To determine the association of central corneal thickness (CCT) and visual field progression in patients with chronic primary angle-closure glaucoma (CPACG) after intraocular pressure (IOP) reduction. Methods: A total of 86 eyes with CPACG and sustained IOP < 21 mmhg were included. The data initial and two-year after Mean Defect (MD) on Humphrey field are analyzed. On the basis of the CCT value, the sample was divided into two groups (group 1 < 540 μm, n = 40 eyes; group 2 ≥ 540 μm, n = 46 eyes). Results: There was no significant difference for initial MD (P = 0.0465) and no significant difference was founded between two groups for follow-up (P = 0.9571). Conclusions: Visual field is not improved after IOP reduction in CPACG with different CCT.

文章引用: 刘 青 (2013) 眼压降低后原发性慢性闭角型青光眼角膜中央厚度和视野损害进展的关系。 眼科学, 2, 39-41. doi: 10.12677/HJO.2013.24009

参考文献

[1] Salmon, J.F., Mermoud, A., Ivey, A., et al. (1993) The prevalence of primary angle closure glaucoma and open angle glaucomain Mamre, Western Cape, South Africa. Archives of Ophthalmology, 111, 1263-1269

[2] 段晓明, 等 (2004) 慢性闭角型青光眼眼压控制稳定后视野变化规律的初步观察. 中国医学科学院学报, 4, 410-414.

[3] Rhee, K., Kim, Y.Y., Nam, D.H., et al. (2001) Comparison of visual field defects between primary open-angle glaucoma and chronic primary angle-closed glaucoma in the early or moderate stage of the disease. Korean Journal of Ophthalmology, 15, 27- 31.

[4] Uchida H., Yamamoto, T., Tomita, G., et al. (1999) Peripapillary atrophy in primary angle-angle glaucoma: A comparative study with primary open-angle glaucoma. American Journal of Ophthalmology, 127, 121-128

[5] 马英慧, 刘刚, 等 (2012) 发性青光眼及高眼压症患者中央角膜厚度的比较研究. 中华实用眼科杂志, 8, 904-905.

[6] Medeiros, F.A., Sample, P.A., Zangwill, L.M., Bowd, C., Aihara, M. and Weinreb, R.N. (2003) Corneal thickness as a risk factor for visual field loss in patients with priperinetric glaucoma atous optic neuropathy. American Journal of Ophthalmology, 136, 805- 813.

[7] Hong, S., Kim, C.Y., Seong, G.J. and Hong, Y.J. (2007) Central corneal thickness and visual field progression in patients with chronic primary angle-closure glaucoma with low intraocular pressure. American Journal of Ophthalmology, 143, 362-363.

[8] 李美玉, 主编 (2004) 青光眼学. 人民卫生出版社, 北京, 252- 253.

[9] Irkec, M.T., Bozkurt, B. and Aslan, U. (2006) Optic nerve head morphometry in Turkish primary open-angle glaucma and ocular hypertensive patients and its correlation with the central corneal thickness. Investigative Ophthalmology & Visual Science, 47, E- Abstract 3409.

[10] 王兰, 王宁利, 等 (2009) 眼压降低后原发性慢性青光眼视野的变化. 眼科研究, 9, 792-795.

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