室温无溶剂无催化剂下的Knoevenagel缩合反应研究
Uncatalyst and Solvent-Free Knoevenagel Condensation Reaction at Room Temperature

作者: 何心伟 , 朱东盛 , 蒋 畅 , 商永嘉 :安徽师范大学,化学与材料科学学院,功能分子固体教育部重点实验室,芜湖;

关键词: Knoevenagel丙二腈缩合反应芳香醛无溶剂反应Knoevenagel Malononitrile Condensation Reactions Aromatic Aldehydes Solvent-Free Reaction

摘要: 本文报道了芳香醛和丙二腈在室温无催化剂无溶剂下的Knoevenagel缩合反应,合成了系列苄叉基化合物,产率良好,并利用1HNMR13CNMR等对合成的化合物结构进行了表征。结果表明,该方法没有使用催化剂和有毒有害的有机溶剂,具有反应条件温和,实验操作及产物后处理简单,产率高,对环境无污染等优点。

Abstract: This paper reported the solvent-free Knoevenagel condensation of aromatic aldehydes and malononitrile at room temperature without catalyst, a series of benzylidene compounds were synthesized in high yields. Structure of all compounds was analyzed by 1HNMR, 13CNMR, and IR. The results showed that this method has advantages of mild reaction conditions and that the operation is simple, convenient post-processing, high yield, and friendly to environment.

文章引用: 何心伟 , 朱东盛 , 蒋 畅 , 商永嘉 (2013) 室温无溶剂无催化剂下的Knoevenagel缩合反应研究。 有机化学研究, 1, 9-12. doi: 10.12677/JOCR.2013.13003

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