柠檬酸钾水溶液热力学性质研究
Thermodynamic Property of Potassium Citrate Solution

作者: 王小芳 * , 樊松林 , 景海权 , 周 芸 :中国石油大港油田分公司石油工程研究院,天津; 朱国强 :中国石油大港油田分公司检测监督评价中心,天津;

关键词: 柠檬酸钾密度粘度表观摩尔体积Potassium Citrate Density Viscosity Apparent Molar Volume

摘要:
柠檬酸钾是目前预防结石常用的一种药物,研究其在水溶液中的扩散具有重要的理论和指导意义。而其水溶液的热力学性质是研究其扩散性质所必需的基础数据。同时,研究相关的热力学性质,可以获得柠檬酸钾在水中的作用及对结石预防和控制的机制。因此,本文研究了柠檬酸钾加量对其水溶液的密度和粘度的影响,并计算得到表观摩尔体积,为生理过程及医疗作用研究提供基础数据。
Potassium citrate nowadays is a pharmaceutical commonly used to prevent calculus. The research of potassium citrate diffusion in aqueous solutions shows significant theoretical and practical meanings. However, it is necessary to research its thermodynamic property which can provided fundamental data for the whole diffusion properties. Meanwhile, the mechanism of preventing and controlling the calculus and the interaction of potassium citrate and water can be obtained by investigation of thermodynamic property. In this work, the influence of potassium citrate solution concentration on density and viscosity were investigated. Based on the density data, the apparent molar volume was calculated at the same time. The results can be utilized as fundamental data for the future research on the medical effect of potassium citrate.

文章引用: 王小芳 , 樊松林 , 朱国强 , 景海权 , 周 芸 (2013) 柠檬酸钾水溶液热力学性质研究。 药物化学, 1, 5-8. doi: 10.12677/HJMCE.2013.11002

参考文献

[1] 李君君. 服用柠檬酸钾前后草酸钙结石患者的尿微晶和尿液性质变化[J]. 无机化学学报, 2012, 28(2): 245-250.

[2] M. G. Bravo-Sánchez. Density and viscosity of aqueous solutions of 1,3-dimethylurea from (288.15 to 333.15) K. Journal of Chemical and Engineering Data, 2009, 55(2): 989-991.

[3] F. A. Sheikh, P. A. Bhat. Effect of temperature and concentration on density, apparent molar volume, ultrasound velocity, iso- entropic compressibility, viscosity, and conductivity of hexade- cyldimethylethyl ammonium bromide. Journal of Chemical and Engineering Data, 2012, 57(12): 3368-3374

[4] P. Novotny, O. Sohnel. Densities of binary aqueous solutions of 306 inorganic substances. Journal of Chemical and Engineering Data, 1988, 33(1): 49-55.

[5] R. Sadeghi, B. Goodarzi and K. Karami. Effect of potassium citrate salts on the transport behavior of l-alanine in aqueous solutions at T = (293.15 to 308.15) K. Journal of Chemical and Engineering Data, 2009, 54(3): 791-794.

[6] F. E. Cohen, M. J. E. Sternberg. On the prediction of protein structure: the significance of the root-mean-square deviation. Journal of molecular biology, 1980, 138(2): 321-333.

[7] F. Millero, R. Horne. Structure and transport process in water and aqueous solutions. New York: RA Horne, 1972.

[8] 申屠雁明, 于养信, 李以圭. 混合电解质溶液的密度和表观摩尔体积的研究[J]. 清华大学学报, 1993, 33(6): 61-72.

[9] R. Pal, E. Rhodes. Viscosity/Concentration Relationships for Emulsions. Journal of Rheology, 1989, 33(7): 1021-1045.

[10] 潘雁, 程时. 高分子烯溶液粘度的浓度依赖性[J]. 高分子通报, 2000, 2: 10-17.

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