Personal Information

Guangwei Liu, MD, PhD, Professor, Department of Immunology, Fudan University.



2004, Ph.D. Jilin University, Changchun, China Immunology

2001, M.D. Jilin University, Changchun, China Medicine



2007-2010, Visiting Scholar, Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN, USA (Autoimmunity and Cell Biology)

2004-2006, Post-doc, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

(Transplant Immunology)



05/2012 – present  Professor

Department of Immunology, Fudan University Shanghai, P.R. China

11/2007 –05/2012  Associate Professor

State Key Laboratory of Biomembrane and Membrane Biotechnology

Institute of Zoology, Chinese Academy of Sciences, Beijing, P.R. China

07/2006 – 11/2007  Assistant Professor

State Key Laboratory of Biomembrane and Membrane Biotechnology

Institute of Zoology, Chinese Academy of Sciences, Beijing, P.R. China

04/2001 – 07/2004  Lector/Assistant Professor

MH Radiobiology Unit, School of Public Health

Jilin University, Changchun, P.R. China.



  1. Guangwei Liu, Xuelian Hu, Bo Sun, Lianfeng Zhang, Yong Zhao (2013). Phosphatase Wip1 negatively regulate neutrophil development and homeostasis through AKT-mTOR. Blood, 121:519-529.
  2. Guangwei Liu (corresponding author), Yujing Bi, Hui Yang, Xianghui Wang (2012). Self-eating and self-defense: autophagy controls innate immunity and adaptive immunity. Journal of Leukocyte Biology, Dec 27.
  3. Guangwei Liu (corresponding author), Hui Yang (2012). Modulation of macrophage activation and programming in immunity. J Cell Physiol.  Doi: 10. 1002/jcp.24157.
  4. T.T. Wu, L. Zhang, K.R. Xu, C. Sun , L. Tong, J. Peng , Guangwei Liu,  R. Wang,  and Y.  Zhao (2012). Immunosuppressive drugs on inducing Ag-specific CD4+CD25+Foxp3+ Treg cells during immune response in vivo, Transplant Immunology, 27: 30-38.
  5. L.J. Zhang, H.B. Zhang, L.L. Li, Y Xiao, E.Y. Rao, H.R. Li, Guangwei Liu, Y Zhao (2012). TSC1/2 signaling complex is essential for peripheral naive CD8+ T cell survival and homeostasis in mice. Plos One, 7(2): e30592.
  6. Bi Y, Guangwei Liu (corresponding author), R.F. Yang (2011). mTOR regulates T-cell differentiation and activation in immunity and autoimmunity. Critical Reviews™ in Eukaryotic Gene Expression. 21: 313-322.
  7. Guangwei Liu, H.X. Ma, Long Li and Y. Zhao (2011). An instructive role of donor macrophages in mixed chimeras in the induction of recipient CD4+Foxp3+ Treg cells. Immunology & Cell Biology. 10.1002/jcp. 22891.
  8. Sun C, Sun L, Ma H, Peng J, Zhen Y, Duan K, Guangwei Liu, Ding W, Zhao Y (2011). The phenotype and functional alterations of macrophages in mice with hyperglycemia for long term. J of Cell Physiol. 227: 1670-1679.
  9. Bi Y, Guangwei Liu (co-first author), R.F. Yang (2011). Reciprocal modulation between TH17 and other helper T cell lineages. J of Cell Physiol. 226: 8-13.
  10. Guangwei Liu, H.X. Ma, L Li, and Y. Zhao (2011). Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+T cells in mice. Immunology & Cell Biology. 89: 130-142.
  11. Guangwei Liu, K. Yang, S. Burns, S. Shrestha, and H.B. Chi (2010). S1P1- mTOR axis directs the reciprocal differentiation of Th1 and regulatory T cells. Nature Immunology, 11: 1047-1056.
  12. Guangwei Liu, L.J. Zhang, and Y. Zhao (2010). Modulation of immune responses through the direct activation of Toll-like receptor to T cells. Clinical & Experimental Immunology, 160: 168-175.
  13. Guangwei Liu, S. Burns, G.H. Huang, K. Boyd, R.L. Poria, R.A. Flavell, and H.B. Chi (2009). The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR. Nature Immunology, 10: 769-777. (See “News and Views” by Ohkura N & Sakaguchi S. Nat Immunol 10:685-686, 2009; and “Research Highlights,” Nat Rev Immunol 9:534, 2009).
  14. Y.J. Bi, Guangwei Liu (corresponding author), and R.F. Yang (2009). MicroRNAs: novel regulators during the immune response. J of Cellular Physiology, 218: 467-472.
  15. H. Shen, G.J. Wu, Guangwei Liu, H.X. Ma, A.Y. Lian, and Y. Zhao (2009). Effects of Rapamycin on the differentiation and function of macrophages in vitro. Agricultural Sciences in China. 8: 620-627.
  16. H.X. Ma, Guangwei Liu, W.J. Ding, Y. Wu, L. Cai, Y. Zhao (2008). Diabetes-induced immunodeficiency of F4/80+ macrophages: a study in streptozotocin-induced type 1 diabetic mice. J of Mol Med, 2008, 86: 391-400.
  17. S.L. Gong, L.H. Dong, Guangwei Liu, P.S. Gong, W.T. Lu, H.G. Zhao, X.J. Jia, Y. Zhao (2008). Effect of corticosterone, cAMP, cGMP, Ca2+ and PKC on apoptosis of thymus lymphocyte in vitro in mice induced by X-irradiation. Biomed and Envir sci. 21:167-72.
  18. Guangwei Liu, P.S Gong, L.R. Berstein, Y. J. Bi, S. L.Gong, Cai L (2007). Apoptotic cell death induced by low-dose radiation in male germ cells: hormesis and adaptation. Crit Rev Toxicol, 37: 587-605.
  19. Guangwei Liu, H.X. Ma, L.L. Jiang, J.X. Peng and Y. Zhao (2007). The immunity of normal F4/80+ resident macrophages in mixed allogeneic chimeras. J of Mol Med, 85: 1125-1135.
  20. Guangwei Liu, Y. Zhao (2007). Toll-like receptors and immune regulation: their direct and indirect modulation on regulatory CD4+CD25+ T cells. Immunology. 122: 149-156.
  21. L. Zhao, H.J. Wang, L.G. Sun, H.X. Ma, Guangwei Liu and Zhao Y (2007). The changes of CD4+CD25+ regulatory T cells in aged mice. J of Leukocyte Biology. 81: 1386-1394. (IF=4.6)
  22. Y.Y. Qu, B.J. Zhang, L. Zhao, Guangwei Liu, H. X. Ma, E. Rao, C. Zeng and Zhao Y (2007). The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice. Transplant Immunology, 17: 153-161.
  23. Guangwei Liu and Y. Zhao (2007). A New subset of CD4+T cells: Th17 and its immunobiological function. Prog in Biochem and Biophy, 34: 125-166.
  24. Guangwei Liu, X.P. Xia, Y. Wu and Y. Zhao (2006). The macrophage heterogeneity: difference between mouse peritoneal exudates and splenic F4/80+ macrophages. J of Cell Physiol, 209: 341-352. (IF=4.5)
  25. Guangwei Liu, H.X. Ma and Y. Zhao (2006). The nonopsonic allogeneic cell phagocytosis of macrophages detected by flow cytometry and two photon fluorescent microscope. Transplant Immunology, 16: 220-226.
  26. Guangwei Liu, C.L. Wu and Y. Zhao (2006). Phagocytosis of apoptotic cells and immune regulation. Scand J of Immunol, 64: 1-9.
  27. Guangwei Liu, Y. Wu, S.L. Gong and Y. Zhao (2006). Toll-like receptors and graft rejection. Transplant Immunology, 16: 25-31.
  28. Guangwei Liu, H.X. Ma and Y. Zhao (2007). Allograft inflammatory factor-1 and transplant reaction. Autoimmunity, 225: 95-102.
  29. Y.J. Bi, Guangwei Liu (corresponding author) and R.F. Yang (2007). Th17 cell induction and immune regulatory effects. J of Cell Physiol, 211: 273-278.
  30. Guangwei Liu, P.S. Gong, H.G. Zhao, Z.C. Wang, S.L. Gong and L. Cai (2006). Effect of low-level radiation on male germ cell death. Radiation Research, 165: 379–389.
  31. Y. Zhao and Guangwei Liu (2006). Specific immune tolerance of antigen- presenting cells: Hypothesis and significance. Medical Hypotheses. 20: 201-204.
  32. S.L. Gong, G. Zhao, H.G. Zhao, W.T. Lu, Guangwei Liu and P. Zhu (2004). Ability of luteinizing hormone releasing hormone-Pseudmonas aeruginosa exotoxin 40 binding to LHRH receptor on human liver cancer cells. World Journal of Gastroenterology, 10: 2870-2873.