Vol.5 No.3 (August 2016)
Research Progress of a New Ocular Drug Delivery System and Its in Vivo and in Vitro Evaluation Methods
Purpose: The purpose is to introduce the progress of ocular drug delivery system and its in vivo and in vitro evaluation methods. Results: Through looking up and summarizing the domestic and foreign literature about ocular drug delivery system in recent years, we find that new ocular drug delivery system is usually about gel system, colloidal particle system, entrapped cyclodextrin complex, etc. Its in vitro evaluation method is mainly in vitro drug release experiment, and the in vivo evaluation methods mainly include ocular residence time and pharmacokinetic study. Conclusion: New type of ocular drug delivery system and its in vivo and in vitro evaluation method are improved. Though there is a certain amount of shortage, they have a very good development prospect.
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