临床医学进展

Vol.6 No.1 (March 2016)

2型糖尿病多器官自身免疫反应机制研究进展
The Research of Type 2 Diabetes Multiorgan Autoimmune Reaction Mechanism

 

作者:

张 琨 :上海中医药大学,上海

寿伟臻 :上海中医药大学附属龙华医院,上海

 

关键词:

2型糖尿病自身免疫反应机制Type 2 Diabetes Autoimmunity Reaction Mechanism

 

摘要:

在糖尿病患者中,2型糖尿病的发病人数占糖尿病总数的90%以上。医学界较统一的观点认为免疫介导的胰岛功能损伤是1型糖尿病的发病机制,胰岛素受体功能缺陷以及受体后信号转导障碍是2型糖尿病的发病机制。但是免疫机制在2型糖尿病的发生以及发展过程中也起着很重要的作用,虽然目前关于这方面的研究还不是很多,但是免疫机制对2型糖尿病重要作用必将成为新的研究热点。

In patients with diabetes, the number of the onset of type 2 diabetes accounts for more than 90% of the total number of diabetes. The medical profession unified a view that immune-mediated islet function damage is the pathogenesis of type 1 diabetes. The function of insulin receptor defects and post receptor signal transduction disorder is the pathogenesis of type 2 diabetes mellitus. But the immune mechanism in the process of the occurrence and development of type 2 diabetes also plays an important role. Though there is not much research on this subject, the immune mechanism of type 2 diabetes important role will become a new research hotspot.

文章引用:

张 琨 , 寿伟臻 (2016) 2型糖尿病多器官自身免疫反应机制研究进展。 临床医学进展, 6, 13-16. doi: 10.12677/ACM.2016.61003

 

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