临床医学进展

Vol.5 No.3 (September 2015)

加味半夏泻心汤治疗迟发性化疗相关性呕吐的临床研究
Clinical Research of Modified Banxiaxiexin for the Treatment of Delayed Chemotherapy-Related Emesis

 

作者:

王海威 :山东省潍坊市中医院,山东 潍坊

赵玮璿 , 崔岩岩 , 贾 玫 :北京中医药大学东直门医院,北京

 

关键词:

加味半夏泻心汤化疗相关性呕吐Modified Banxiaxiexin Chemotherapy-Induced Vomiting

 

摘要:

目的:观察加味半夏泻心汤治疗迟发性化疗相关性呕吐的疗效。方法:通过随机对照研究方法,以呕吐程度量表、中医症状积分量表为观察指标,将迟发性化疗相关性呕吐患者45例随机分为对照组22例,治疗组23例,全部病例连续治疗5天。分别于治疗第1天、第6天采集临床数据。结果:治疗组与对照组总有效率为82.61%:81.82%,P > 0.05,无统计学意义。分层分析发现,治疗组在改善患者恶心呕吐、胃脘痞满、纳呆症状明显优于对照组,P < 0.05,有统计学意义。结论:加味半夏泻心汤能在一定程度上减轻迟发性化疗相关性呕吐的临床症状。

Object: The object of this clinical trial is to evaluate the clinical efficacy of Modified Banxiaxiexin Soup for the treatment of patients with delayed chemotherapy-induced vomiting. Methods: By pragmatic randomized controlled study, we observed 45 patients with delayed chemotherapy- induced vomiting, of which 22 cases in the control group and 23 cases in the treatment group, both groups received five consecutive days of treatment. Two groups of patients were respectively ob-served on the first day and the six day of treatment and they were requested to fill vomiting grading scale and TCM symptom score scale. Results: After treatment in terms of the degree of vomiting, the total effective rate was 82.61% in the treatment group, while the control group was 81.82%, the difference was not statistically significant (P > 0.05). By stratified analysis, if found that the treatment group in improving patients nausea and vomiting was better than the control group. The difference was statistically significant (P < 0.05). Conclusion: Modified Banxiaxiexin Soup can reduce the clinical symptoms in patients with delayed chemotherapy-in- duced vomiting to some extent and improve the quality of life of them.

文章引用:

王海威 , 赵玮璿 , 崔岩岩 , 贾 玫 (2015) 加味半夏泻心汤治疗迟发性化疗相关性呕吐的临床研究。 临床医学进展, 5, 193-197. doi: 10.12677/ACM.2015.53031

 

参考文献

分享
Top