计算生物学

Vol.5 No.3 (September 2015)

基于RiceWiki的水稻抗逆基因审编与分析
The Curation and Analysis of Rice Stress-Resistance Genes Based on RiceWiki

 

作者:

张烨 , 陈玲玲 :华中农业大学信息学院,湖北 武汉

章张 :中国科学院北京基因组研究所基因组科学与信息重点实验室,北京

 

关键词:

RiceWiki审编抗逆性RiceWiki Curation Stress-Resistance

 

摘要:

在中国,审编是一个新领域,对各种生物学信息进行审编是今后的发展趋势。本文收集了文献中耐盐、耐旱、耐热、耐寒、抗植株矮小、抗倒伏、抗白叶枯病、抗稻瘟病这8种水稻抗逆基因,共计500个。以RiceWiki为平台,对搜集的水稻抗逆基因进行审编,发布到RiceWiki上,并对搜集的500个基因进行了分析。首先分析了抗逆基因之间的蛋白互作,得到了61个蛋白质间的78个蛋白互作。共表达分析表明有明显共表达趋势的蛋白对占21.61%,进一步表明了这些抗逆基因编码的蛋白可以互作。最后,利用argiGO对GO富集度进行了分析,结果表明和压力相关的GO语义的显著性水平较高。

Curation is a frontier in China, the biocuration of all kinds of biological information is the devel-opment tendency. In this paper, 500 rice genes of eight kinds stress-resistance were collected from literature: salinity tolerance, drought tolerance, cold tolerance, heat tolerance, dwarf resis-tance, lodging resistance, bacterial blight resistance and blast resistance. Curating the rice stress- resistance genes based on the platform of RiceWiki and publishing on RiceWiki. The 500 rice stress-resistance genes were further analyzed. First, the protein-protein interactions between stress-resistance rice genes were analyzed which containing 78 protein interactions among 61 proteins. The results of co-expression analysis indicated that 21.61% protein pairs have a tendency to co-expression, which showed the protein encoded by the stress-resistance genes could interact with each other. Finally, the GO enrichment is analyzed by argiGO, the results indicated that the significant level of GO terms related to stress is higher.



文章引用:

张烨 , 陈玲玲 , 章张 (2015) 基于RiceWiki的水稻抗逆基因审编与分析。 计算生物学, 5, 29-40. doi: 10.12677/HJCB.2015.53004

 

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