临床医学进展

Vol.5 No.2 (June 2015)

肿瘤预后相关免疫抑制分子概述
The Overview of Tumor-Related Immunosuppressive Molecules

 

作者:

张冬云 , 刘安丽 , 李 寅 , 王 静 :南阳医学高等专科学校,基础医学部,河南 南阳

刘 冉 :南阳医学高等专科学校,第一附属医院肿瘤科,河南 南阳

 

关键词:

肿瘤免疫免疫抑制分子综述Tumor Immune Immunosuppressive Molecules Overview

 

摘要:

肿瘤机体内免疫抑制细胞、免疫抑制分子状态与肿瘤发生、发展密切相关。本文综述了肿瘤免疫过程中参与肿瘤免疫逃逸的免疫抑制分子PD-1,CTLA-4,TIM-3,LAG-3,CD160,BTLA的功能状况及最新研究进展。

Tumorigenesis was closely related to the states of immune tumor suppressor cells and immuno-suppressive molecules. In the paper, we overviewed current functional situation and newly re-search progress of immunosuppressive molecules, e.g. programmed death-1, cytotoxic T lympho-cyte-associated antigen-4, T cell immunoglobulin domain and mucin domain-3, B and T lymphocyte attenuator, LAG-3, CD160, which took part in the tumor immune escape in the process of tumor immunity.

文章引用:

张冬云 , 刘 冉 , 刘安丽 , 李 寅 , 王 静 (2015) 肿瘤预后相关免疫抑制分子概述。 临床医学进展, 5, 78-83. doi: 10.12677/ACM.2015.52014

 

参考文献

分享
Top