Vol.4 No.4 (December 2014)
Typing, Risk Factors and Related Treatments of Cholangiocarcinoma
Cholangiocarcinoma (CCA), is a highly malignant tumor, clinically rare and accounting for less than 1% of all malignant tumors. But the number of patients with cholangiocarcinoma in China increases year by year, so cholangiocarcinoma research has special significance in our country. Depending on the anatomical location, cholangiocarcinoma is divided into: hilar cholangiocarcinoma (PHC), the distal bile duct (DCCA) and intrahepatic cholangiocarcinoma (ICCA), among which hilar is the most common. Currently, surgery is the best treatment, but because early diagnosis is difficult, most cases are in the end-stage when diagnosed; therefore, less than 10% of patients are able to tolerate surgery. However the high recurrence rate and low survival rate are still unresolved. With clinical treatment of cholangiocarcinoma deepening, new treatments gradually formed. This article summarizes the results of the analysis of the cholangiocarcinoma typing, clinical manifestations, risk factors, molecular biological mechanisms and related treatment.
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