Vol.3 No.4 (December 2013)
The Diagnosis and Differential Diagnosis of Nodular Lymphocyte Predominant Hodgkin Lymphoma(NLPHL)
李 青 ：新疆伊犁哈萨克自治州妇幼保健院病理科，伊宁;南京医科大学附属南京市妇幼保健院病理科，南京
Objective: The aim of this paper is to make the accurate classification of Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), because every type of NLPHL has its distinct therapeutic and prognostic implications. Methods: To diagnose NLPHL and make clear the differential diagnosis among NLPHL, classical Hodgkin lymphoma, T-cell/histiocyte-rich large B-cell lymphoma, follicular lymphoma (floral variant), and follicular hyperplasia with progressive transformation of germinal centers, histologic and immunophenotypic features were analyzed. Results: With the morphologic and IHC phenotype, the diagnosis of NHPHL can be made on excisional biopsies. Conclusion: Clinical, histologic, and IHC features are essential in accurate diagnosis of NLPHL.
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